CD4 anticorps (PE)

N° du produit ABIN6657902

N° du produit (Fournisseur): 200-508-m70

Cet anticorps anti-CD4 est un anticorps Rat Monoclonal détectant CD4 dans FACS et FM. Adapté pour Souris.

Aperçu rapide pour CD4 anticorps (PE) (ABIN6657902)

Antigène: CD4

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD4 est conjugé à/à la PE

Application: Flow Cytometry (FACS), Fluorescence Microscopy (FM)

Clone: GK1-5

Détail du produit anti-CD4 anticorps (PE)

N° du produit (Fournisseur): 200-508-m70

Fournisseur: Rockland

Fonction: CD4 Phycoerythrin Antibody

Réactivité croisée (Details): Reactivity is observed against mouse CD4.

Purification: Phycoerythrin conjugated CD4 Monoclonal Antibody was Protein G Purified and is directed against mouse CD4.

Stérilité: Sterile filtered

Immunogène: Anti-CD4 Antibody (Monoclonal) was produced by repeated immunizations with Mouse CTL clone V4.

Isotype: IgG2b kappa

Labeling Ratio: 1-2

Information d'application

Indications d'application:

Flow_Cytometry_Dilution: 0.1-1 μg/10^6 cells

IF_Microscopy_Dilution: User Optimized

Commentaires:

Anti-CD4 is tested for Flow Cytometry (Cell Surface) and useful for Immunofluorescence. Researchers should determine optimal titers for applications that are not stated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.05 % BSA

Preservative: 0.09 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

Date de péremption: 6 months

Détails sur CD4

Antigène: CD4

Autre désignation: CD4

Sujet:

Synonyms: T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4 Antibody, L3T4, T4

Background: CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It is a member of the immunoglobulin superfamily. On T cells, it is the co-receptor for the T cell receptor (TCR) and amplifies the signal generated by the TCR by recruiting the tyrosine kinase lck that is essential for activating many molecules involved in the signaling cascade of an activated T cell. It is an important component of the immune system and is also the cellular receptor for HIV-1. It consists of a cytoplasmic tail, one transmembrane region, and four extracellular domains, D1-D4.  It maps to 12pter-p12 region of human chromosome.

Gene Name: CD4

ID gène: 12504

NCBI Accession: NP_038516

UniProt: P06332

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events